1H-Indazol-3-aMine, 5-broMo-7-Methyl-

1H-Indazol-3-aMine, 5-broMo-7-Methyl- - Names and Identifiers

Name	1H-Indazol-3-amine, 5-bromo-7-methyl-
Synonyms	5-Bromo-7-methyl-1H-indazol-3-amine 5-bromo-7-methyl-1H-indazol-3-amine 5-broMo-7-Methyl-3-AMino-1H-indazole 1H-Indazol-3-amine, 5-bromo-7-methyl- 1H-Indazol-3-aMine, 5-broMo-7-Methyl-
CAS	1110502-50-5

1H-Indazol-3-aMine, 5-broMo-7-Methyl- - Physico-chemical Properties

Molecular Formula	C8H8BrN3
Molar Mass	226.07322
Boling Point
Storage Condition	Room Temprature

1H-Indazol-3-aMine, 5-broMo-7-Methyl- - Introduction

3-amine-5-bromo-7-methyl-1H-indazole is an organic compound with the chemical formula C9H9BrN2.

Nature:
-Appearance: Colorless crystalline solid.
-Melting point: approximately 148°C.
-Boiling point: approximately 390°C.
-Density: 1.77g/cm³.
-Solubility: Soluble in organic solvents such as chloroform, alcohol and benzene.

Use:
- 3-amine -5-bromo -7-methyl -1H-indazole can be used as an intermediate in organic synthesis, commonly used in the preparation of other compounds, such as organic dyes, pharmaceutical intermediates.

Preparation Method:
3-amine-5-bromo-7-methyl-1H-indazole can be prepared by the following steps:
1. in methyl chloride or dichloromethane, 2-bromo -3-amino pyridine and 3-amino -5-bromine pyrazole reaction.
2. add sodium nitrite solution and continue the reaction.
3. adding formaldehyde and a catalyst to catalyze the reaction to obtain 3-amine -5-bromo -7-methyl -1H-indazole.
4. The product is purified by crystallization or column chromatography.

Safety Information:
- 3-amine -5-bromo -7-methyl -1H-indazole has certain toxicity, when using to wear protective gloves, protective glasses, etc.
-Avoid contact with skin and inhalation of dust or gas.
-When stored, it should be sealed and kept in a cool and dry place, away from fire and flammable materials.
-Please read the relevant safety instructions carefully before use, and refer to the relevant regulations and operating procedures for operation.

Last Update：2024-04-09 02:00:41